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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.mrfmmm.2008.08.009
DC FieldValue
dc.titleTranscriptional and epigenetic regulations of embryonic stem cells
dc.contributor.authorNg, J.-H.
dc.contributor.authorHeng, J.-C.D.
dc.contributor.authorLoh, Y.-H.
dc.contributor.authorNg, H.-H.
dc.date.accessioned2014-10-27T08:49:41Z
dc.date.available2014-10-27T08:49:41Z
dc.date.issued2008-12-01
dc.identifier.citationNg, J.-H., Heng, J.-C.D., Loh, Y.-H., Ng, H.-H. (2008-12-01). Transcriptional and epigenetic regulations of embryonic stem cells. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 647 (1-2) : 52-58. ScholarBank@NUS Repository. https://doi.org/10.1016/j.mrfmmm.2008.08.009
dc.identifier.issn00275107
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/102575
dc.description.abstractEmbryonic stem cells (ESCs) are characterized by their broad developmental potential and the capacity to self-renew. The advent of high-throughput technologies has facilitated genome-wide studies of transcriptional network, resulting in an ever-increasing repertoire of transcription factors implicated in the maintenance of the embryonic stem cell state. While the transcriptional circuitry continues to expand, epigenetic regulation has also gained attention as an important process in stem cell function. Herein, we discuss the recent advancements made in understanding the transcriptional and epigenetic regulations of embryonic stem cells. © 2008.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.mrfmmm.2008.08.009
dc.sourceScopus
dc.subjectEmbryonic stem cell
dc.subjectEpigenetics
dc.subjectPluripotency
dc.subjectSelf-renewal
dc.subjectTranscriptional regulatory network
dc.typeReview
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1016/j.mrfmmm.2008.08.009
dc.description.sourcetitleMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
dc.description.volume647
dc.description.issue1-2
dc.description.page52-58
dc.description.codenMRFME
dc.identifier.isiut000261703600008
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