Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.bbagrm.2011.06.009
Title: | Choreographing pluripotency and cell fate with transcription factors | Authors: | Gonzales, K.A.U. Ng, H.-H. |
Keywords: | Pluripotency Reprogramming Stem cell Transcription factor Transdifferentiation |
Issue Date: | Jul-2011 | Citation: | Gonzales, K.A.U., Ng, H.-H. (2011-07). Choreographing pluripotency and cell fate with transcription factors. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1809 (7) : 337-349. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbagrm.2011.06.009 | Abstract: | The cellular identity of both pluripotent and differentiated cells is defined by the concerted interplay of transcriptional factors as well as other modulators such as epigenetic and signaling mediators. Therefore, the manipulation of a cell's transcriptional network directly facilitates inter-conversion between cellular identities. Understanding the molecular regulation of cell fate changes, including those involved in pluripotency, is crucial in realizing the practical potential of pluripotent and induced cell types. Here we review the advancements in the role of transcription factors in pluripotency, as well as in the conversion between and within pluripotent and somatic cell types. © 2011 Elsevier B.V. | Source Title: | Biochimica et Biophysica Acta - Gene Regulatory Mechanisms | URI: | http://scholarbank.nus.edu.sg/handle/10635/102418 | ISSN: | 18749399 | DOI: | 10.1016/j.bbagrm.2011.06.009 |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.