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|Title:||Genome-wide identification of female-enriched genes in zebrafish|
|Citation:||Wen, C., Zhang, Z., Ma, W., Xu, M., Wen, Z., Peng, J. (2005-01). Genome-wide identification of female-enriched genes in zebrafish. Developmental Dynamics 232 (1) : 171-179. ScholarBank@NUS Repository. https://doi.org/10.1002/dvdy.20210|
|Abstract:||Characteristic differences in morphology, physiology, and behavior between a male and female are correlated to the differential selection of sex-dependent transcriptomes. By using a cDNA array carrying -9,000 zebrafish unique genes, we identified a group of genes whose expression are enriched in the female fish. A subset of these genes have been confirmed and further grouped as egg-enriched genes, as both somatic- and egg-enriched genes or as somatic-enriched genes by means of RNA gel blot hybridization. Most importantly, a significant proportion of these genes are either functionally unknown or are novel genes. Thus, future studies of this group of genes will help us greatly to understand more about sex-determination and sex-related physiology and behavior. In addition, comparison of zebrafish female-enriched genes with that in Drosophila, we found that only germline genes are shared between vertebrate and invertebrate, suggesting that the process of oogenesis is highly conserved during the evolution. © 2004 Wiley-Liss, Inc.|
|Source Title:||Developmental Dynamics|
|Appears in Collections:||Staff Publications|
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