Please use this identifier to cite or link to this item:
|Title:||Crystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom|
|Citation:||Banerjee, Y., Kumar, S., Jobichen, C., Kini, R.M. (2007-07-28). Crystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63 (8) : 701-703. ScholarBank@NUS Repository. https://doi.org/10.1107/S1744309107034239|
|Abstract:||Hemextin A was isolated and purified from African Ringhals cobra (Hemachatus haemachatus). It is a three-finger toxin that specifically inhibits blood coagulation factor VIIa and clot formation and that also interacts with hemextin B to form a unique anticoagulant complex. Hemextin A was crystallized by the hanging-drop vapour-diffusion method by equilibration against 0.2 M ammonium acetate, 0.1 M sodium acetate trihydrate pH 4.6 and 30% PEG 4000 as the precipitating agent. The crystals belong to space group P212 121, with unit-cell parameters a = 49.27, b = 49.51, c = 57.87 Å and two molecules in the asymmetric unit. They diffracted to 1.5 Å resolution at beamline X25 at BNL. © International Union of Crystallography 2007.|
|Source Title:||Acta Crystallographica Section F: Structural Biology and Crystallization Communications|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 14, 2018
WEB OF SCIENCETM
checked on Jun 19, 2018
checked on Jul 6, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.