Please use this identifier to cite or link to this item: https://doi.org/10.1107/S1744309107034239
Title: Crystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom
Authors: Banerjee, Y.
Kumar, S. 
Jobichen, C. 
Kini, R.M. 
Keywords: Anticoagulants
Hemextin
Snake-venom toxins
Three-finger toxins
Issue Date: 28-Jul-2007
Citation: Banerjee, Y., Kumar, S., Jobichen, C., Kini, R.M. (2007-07-28). Crystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63 (8) : 701-703. ScholarBank@NUS Repository. https://doi.org/10.1107/S1744309107034239
Abstract: Hemextin A was isolated and purified from African Ringhals cobra (Hemachatus haemachatus). It is a three-finger toxin that specifically inhibits blood coagulation factor VIIa and clot formation and that also interacts with hemextin B to form a unique anticoagulant complex. Hemextin A was crystallized by the hanging-drop vapour-diffusion method by equilibration against 0.2 M ammonium acetate, 0.1 M sodium acetate trihydrate pH 4.6 and 30% PEG 4000 as the precipitating agent. The crystals belong to space group P212 121, with unit-cell parameters a = 49.27, b = 49.51, c = 57.87 Å and two molecules in the asymmetric unit. They diffracted to 1.5 Å resolution at beamline X25 at BNL. © International Union of Crystallography 2007.
Source Title: Acta Crystallographica Section F: Structural Biology and Crystallization Communications
URI: http://scholarbank.nus.edu.sg/handle/10635/100375
ISSN: 17443091
DOI: 10.1107/S1744309107034239
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

3
checked on Nov 13, 2018

WEB OF SCIENCETM
Citations

2
checked on Nov 13, 2018

Page view(s)

27
checked on Oct 19, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.