Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/100095
Title: Anticoagulant venom and mammalian secreted phospholipases A2: Protein- versus phospholipid-dependent mechanism of action
Authors: Mounier, C.M.
Bon, C.
Kini, R.M. 
Keywords: Anticoagulant
Factor Va
Factor Xa
Mammalian
Secreted phospholipase A2
Snake venom
Issue Date: 2001
Citation: Mounier, C.M.,Bon, C.,Kini, R.M. (2001). Anticoagulant venom and mammalian secreted phospholipases A2: Protein- versus phospholipid-dependent mechanism of action. Haemostasis 31 (3-6) : 279-287. ScholarBank@NUS Repository.
Abstract: Some venom and mammalian-secreted phospholipases A2 (sPLA2) have been described to exert an anticoagulant effect. This review will discuss and compare phospholipid-dependent versus protein-dependent mechanisms of action of these sPLA2 on the coagulation cascade. The importance of venom proteins, and of the study of their pharmacological effects, to explore the physiological functions of homologous mammalian proteins is also pointed out. Copyright © 2002 S. Karger AG, Basel.
Source Title: Haemostasis
URI: http://scholarbank.nus.edu.sg/handle/10635/100095
ISSN: 03010147
Appears in Collections:Staff Publications

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